ANAGRELIDE HYDROCHLORIDE
Anagrelide Hydrochloride
CAS: 58579-51-4
Molecular Formula: C10H8Cl3N3O
ANAGRELIDE HYDROCHLORIDE - Names and Identifiers
| Name | Anagrelide Hydrochloride |
| Synonyms | AGRYLIN BL-4162A BMY-26538-01 ANAGRELIDE HCL Anagrelide hcl Anagrelide Hydrochloride ANAGRELIDE HYDROCHLORIDE AnagrelideHclC10H7C12N30.HC1 1-b)quinazolin-2(3h)-one,6,7-dichloro-1,5-dihydro-imidazo(monohydrochlorid 6,7-Dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one monohydrochloride 6,7-DICHLORO-1,5-DIHYDROIMIDAZO[2,1-B]QUINAZOLIN-2(3H)-ONE MONOHYDROCHLORIDE 6,7-Dichloro-1,5-dihydroimidazo(2,1-b)-quinazolin-2(3H)-one monohydrochloride |
| CAS | 58579-51-4 |
| EINECS | 680-360-9 |
| InChI | InChI=1/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;/h1-2H,3-4H2,(H,13,14,16);1H |
ANAGRELIDE HYDROCHLORIDE - Physico-chemical Properties
| Molecular Formula | C10H8Cl3N3O |
| Molar Mass | 292.55 |
| Melting Point | >280°C |
| Boling Point | 376.5°C at 760 mmHg |
| Flash Point | 181.5°C |
| Solubility | DMSO: soluble1mg/mL, clear (warmed) |
| Vapor Presure | 7.21E-06mmHg at 25°C |
| Appearance | powder |
| Color | white to beige |
| Storage Condition | 2-8°C |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| Use | Anagrelide HCl is a drug for the treatment of essential thrombocytosis. It is an oral imidazoquinazoline agent with anti-cyclic adenylate phosphodiesterase activity and can inhibit platelet aggregation in humans and animals. Anagrelide works by inhibiting the maturation of megakaryocytes into platelets. |
| In vivo study | Anagrelide is an orally administered imidazoquinazoline agent that has activity against cyclic adenosine monophosphate phosphodiesterase and inhibits platelet aggregation in both humans and animals. Anagrelide acts by inhibiting the maturation of megakaryocytes into platelets. |
ANAGRELIDE HYDROCHLORIDE - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
ANAGRELIDE HYDROCHLORIDE - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 3.418 ml | 17.091 ml | 34.182 ml |
| 5 mM | 0.684 ml | 3.418 ml | 6.836 ml |
| 10 mM | 0.342 ml | 1.709 ml | 3.418 ml |
| 5 mM | 0.068 ml | 0.342 ml | 0.684 ml |
Last Update：2024-01-02 23:10:35
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View History
ANAGRELIDE HYDROCHLORIDE
Carbamic acid, [4-(hydroxymethyl)bicyclo[2.2.2]oct-1-yl]-, phenylmethyl ester (9CI)
BOC-11-AMINOUNDECANOIC ACID
2-氯-4-三氟甲基-5-溴嘧啶
苯甲基 3-碘吖丁啶-1-甲酸基酯
boc-tyr-gly-gly-phe-leu-arg-arg-ile-arg-pro-arg-leu-arg-gly 5-aminopentylamide
(CARBETHOXYMETHYL-1,2-13C2)TRIPHENYLPHOSPHONIUM BROMIDE
二聚季戊四醇六辛酸酯/六癸酸酯
SODIUM CHLORIDE
3-((2-氨基-3-氯吡啶-4-基)硫基)-6-氯吡嗪-2-胺
Carbamic acid, [4-(hydroxymethyl)bicyclo[2.2.2]oct-1-yl]-, phenylmethyl ester (9CI)
BOC-11-AMINOUNDECANOIC ACID
2-氯-4-三氟甲基-5-溴嘧啶
苯甲基 3-碘吖丁啶-1-甲酸基酯
boc-tyr-gly-gly-phe-leu-arg-arg-ile-arg-pro-arg-leu-arg-gly 5-aminopentylamide
(CARBETHOXYMETHYL-1,2-13C2)TRIPHENYLPHOSPHONIUM BROMIDE
二聚季戊四醇六辛酸酯/六癸酸酯
SODIUM CHLORIDE
3-((2-氨基-3-氯吡啶-4-基)硫基)-6-氯吡嗪-2-胺